Our analysts evaluate clinical trial data, along with information regarding safety issues, coverage policies from the private and public sectors, regulatory approvals, consensus statements, and an overall projection of the potential clinical efficacy and economic impact of the technology. Reports are reviewed annually up to 5 years post publication to determine if there is new literature or evidence that would impact a change in rating and warrant an updated report.
Focus of the Report: Use of oral immunotherapy (OIT) with Palforzia (formerly AR101) for the management of peanut allergy.
Technology Description: Palforzia (peanut allergen powder-dnfp) is an oral immunotherapy (OIT) treatment comprising a proprietary formulation of peanut protein man…
Focus of the Report: In its application to prostate biopsy, micro-ultrasound (mUS), also known as high-resolution ultrasound (US), not only provides guidance for the biopsy needle but also allows identification of features that cannot be revealed by conventional US. Thus, mUS has the potential to identify cancerous lesions that might otherwis…
Focus of the Report: In its application to prostate biopsy, micro-ultrasound (mUS), also known as high-resolution ultrasound (US), not only provides guidance for the biopsy needle but also allows identification of features that cannot be revealed by conventional US. Thus, mUS has the potential to identify cancerous lesions that might otherwis…
Focus of the Report: For use of botulinum toxin (BTX) for Raynaud phenomenon (RP).
Technology Description: BTX has been investigated as a treatment for various chronic painful conditions because of its potential to reduce muscle tension and modulate pain receptor activity in the central nervous system. For the treatment of RP, there is currently no sta…
Focus of the Report: Implantation of the ProACT device for the treatment of adult men with post-prostate surgery urinary incontinence (UI).
Technology Description: The ProACT system is a medical implantable device that consists of 2 sets of urethral balloons connected to titanium volume adjustment ports via tubing. During ProACT device implantation, a …
Focus of the Report: The use of transabdominal cervical cerclage (TAC) for treatment of cervical insufficiency to prevent preterm delivery (PTD) or miscarriage.
Technology Description: TAC involves the placement of sutures to reinforce the cervix using a transabdominal approach. An al…
Focus of the Report: Magnetic resonance elastography (MRE) is a diagnostic test for assessing hepatic fibrosis, a form of liver damage that occurs when healthy tissue is replaced by stiff, fibrous scar tissue. This report focuses on MRE for prediction of serious potential consequences of liver disease such as development of cirrhosis or liver…
Focus of the Report: The use of Scrambler therapy (ST), also referred to as Calmare Pain Therapy and transcutaneous electrical modulation pain reprocessing (Calmare Therapeutics Inc.), for the management of chronic pain not related to cancer or cancer treatments.
Technology Description: ST is a noninvasive, transdermal treatment for the symptomatic rel…
Focus of the Report: Use of Scrambler therapy (ST), also referred to as Calmare Pain Therapy and transcutaneous electrical modulation pain reprocessing (Calmare Therapeutics Inc.), for the management of chronic pain related to cancer or cancer treatment.
Technology Description: ST is a…
Focus of the Report: The focus of the report is on the use of ovarian or internal iliac vein embolization for the treatment of pelvic congestion syndrome (PCS).
Technology Description: Embolization is intended to block the blood supply to the enlarged or swollen veins associated with P…