Our analysts evaluate clinical trial data, along with information regarding safety issues, coverage policies from the private and public sectors, regulatory approvals, consensus statements, and an overall projection of the potential clinical efficacy and economic impact of the technology. Reports are reviewed annually up to 5 years post publication to determine if there is new literature or evidence that would impact a change in rating and warrant an updated report.
Focus of the Report: The focus of this report is phacocanaloplasty (P-CP) for the treatment of concomitant open-angle glaucoma (OAG) and cataract in adult patients.
Technology Description: P-CP combines phacoemulsification (phaco), the standard care cataract extraction and intraocular …
Focus of the Report: This report evaluates cooled radiofrequency ablation (CRFA) using the Coolief Cooled Radiofrequency system (Avanos Medical Inc.) for pain associated with knee osteoarthritis (KOA).
Technology Description: CRFA is intended to use less heat than conventional radiofre…
Focus of the Report: This report evaluates cooled radiofrequency ablation (CRFA) using the Coolief Cooled Radiofrequency system (Avanos Medical Inc.) for pain associated with knee osteoarthritis (KOA).
Technology Description: CRFA is intended to use less heat than conventional radiofre…
Focus of Report: Laser interstitial thermal therapy (LITT) with real-time magnetic resonance imaging thermography is being investigated as a minimally invasive surgical alternative for treatment of mesial refractory temporal lobe epilepsy (MTLE).
Technology Description: LITT delivers …
Health Problem: Epilepsy is one of the most common neurological disorders in the United States and has a prevalence of approximately 3 million adults and 470,000 children. Management generally involves treatment with antiepileptic drugs (AEDs), but for approximately 30% of patients, seizures will remain uncontrolled by medical therapy. In the…
Health Problem: Flatfoot (FF) refers to a progressive developmental or acquired deformity characterized by plantar medial rotation of the talus, decrease in medial arch height, and abduction of the forefoot. In children, FF may be an isolated clinical entity or it may be found with neuromuscular disorders (e.g., cerebral palsy [CP]). Untreate…
Health Problem: Dry eye disease (DED) is a type of ocular surface disorder. Meibomian gland dysfunction (MGD) contributes to DED in approximately 60% of patients. The meibomian glands (MGs) are present in the upper and lower eyelids and they secrete lipids that are an important component of tears. The oily lipids float to the surface of tear …
Health Problem: Diabetes mellitus (DM) is a chronic, progressive disease characterized by impaired metabolism of carbohydrates. DM affects approximately 30 million Americans (9.4% of the population) and costs $327 billion annually in the United States.
Technology Description: The OmniP…
Health Problem: Glaucoma is a disease of the optic nerve characterized by loss of retinal ganglion cells; remodeling of the lamina cribrosa; structural changes to the nerve; elevated intraocular pressure (IOP); and progressive, irreversible loss of vision leading to blindness. Open-angle glaucoma (OAG) is associated with partial blockage of t…
Health Problem: Chordomas are rare primary bone tumors originating from remnants of the embryonic notochord and most commonly arising in the skull base (32%), mobile spine (33%), and sacrum (29%). Chondrosarcomas, which arise from cartilage, are usually low-grade, indolent, invasive tumors that cause morbidity by compressing skull base neurov…