Our analysts evaluate clinical trial data, along with information regarding safety issues, coverage policies from the private and public sectors, regulatory approvals, consensus statements, and an overall projection of the potential clinical efficacy and economic impact of the technology. Reports are reviewed annually up to 5 years post publication to determine if there is new literature or evidence that would impact a change in rating and warrant an updated report.
Purpose of Technology
The second-wave direct-acting antivirals (DAAs) are prescribed to treat chronic hepatitis C with the objective of achieving sustained viral response and preventing harmful liver damage. These agents were developed to address the issues…
Purpose of Technology
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are monoclonal antibodies that target and inactivate the PCSK9 protein in the liver. This drug is intended to reduce the amount of harmful low-density lipoprotein cholesterol (LDL-C) circulating in the bloodstream,…
Purpose of Technology
Low-intensity pulsed ultrasound (US) bone growth stimulators apply low-intensity, pulsed, high-frequency acoustic pressure waves to a fracture site to stimulate bone growth and promote fracture healing. Bone growth stimulators have been developed to augment standard operative an…
Purpose of Technology
Continuous glucose monitoring (CGM) systems are minimally invasive or noninvasive devices that measure glucose levels in interstitial fluid at frequent intervals over a period of several days. CGM systems are designed to obtain information regarding daily patterns in glucose levels that, when evaluated in re…
Intensity modulated radiation therapy (IMRT) is an advanced type of conformal radiation therapy for anal, rectal, and other cancers in which computer software modulates the radiation dose so that the tumor f…
Negative pressure wound therapy (NPWT) is a treatment for acute, subacute, and chronic wounds that involves the application of subatmospheric pressure to the open wound with the goal of creating a controlled…
Purpose of Technology
A pacemaker is a small, battery-powered device, typically implanted under the skin in the chest near the collarbone, with wires leading directly to the ventricle(s) and/or atrium(a) of the heart. These devices treat cardiac arrhythmias…