This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of intravascular lithotripsy (IVL) for treatment of calcified arteries in patients with coronary artery disease (CAD).
Evidence Analysis
It is a challenge for health plans and clinicians to distill and analyze volumes of clinical evidence to determine likely clinical, financial, and risk impacts. This is what we do.Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:
- Does the technology improve health outcomes?
- Are there other benefits associated with the technology?
- What harms might be associated with the technology?
- Have patient selection criteria been established for the technology?
- For which patients might the technology provide a benefit?
- Health Technology Assessments
- Evidence Analysis Research Briefs
- Evolving Evidence Review
- Clinical Research Responses
Fecal Calprotectin Assay for Monitoring Disease Activity and Treatment Management of Ulcerative Colitis in Adults
Focus of the Report: This report focuses on fecal calprotectin (FC) testing to monitor disease activity and guide therapy choices in patients who have ulcerative colitis (UC).
Technology Description: Calprotectin is a calcium-binding protein that is abundant in neutrophils. During acti…
Fecal Calprotectin for Predicting Clinical Relapse or Treatment Response in Adult Patients with Ulcerative Colitis
Focus of the Report: This report focuses on fecal calprotectin (FC) testing for determining the prognosis of disease activity (i.e., predicting clinical relapse) in patients who are undergoing treatment for ulcerative colitis (UC).
Technology Description: Calprotectin is a calcium-bind…
Fecal Microbiota Transplantation for the Treatment of Ulcerative Colitis
Focus of the Report: This report focuses on the use of fecal microbiota transplantation (FMT) to treat adults with ulcerative colitis (UC).
Technology Description: FMT is a procedure by which processed stool from healthy donors is infused into a patient’s gastrointestinal (GI) system for the purpose of treating a disease associated with impaired gut mi…
Ellipsys Vascular Access System (Avenu Medical) in Patients with End-Stage Renal Disease
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the Ellipsys Vascular Access System (VAS) for the creation of arteriovenous fistula (AVF) in patients who undergo hemodialysis.
Intravenous Immunoglobulin (IVIG) for Treatment of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of intravenous immunoglobulin (IVIG) for treatment of pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS).
Triamcinolone Acetonide Extended-Release (Zilretta) for the Management of Knee Osteoarthritis
Focus of the Report: The use of Zilretta (triamcinolone acetonide extended-release injectable suspension) for the treatment of pain associated with knee osteoarthritis (KOA).
Technology Description: Zilretta (Flexion Therapeutics Inc.) is an extended-release intra-articular therapy for pat…
Radiofrequency Ablation for Benign Thyroid Nodules
Focus of the Report: This report focuses on the use of radiofrequency ablation (RFA) for treatment of symptomatic benign thyroid nodules (BTNs) in adult patients.
Technology Description: RFA is an ultrasound (US)-guided, minimally invasive treatment approach, which applies high frequen…
Annular Closure for Prevention of Lumbar Disc Reherniation
Focus of the Report: This report focuses on annular closure for the prevention of recurrent lumbar disc herniation (LDH) after lumbar discectomy (LD).
Technology Description: Annular closure is a surgical treatment that is performed immediately following an LDH debridement surgery (e.g., l…
Botulinum Toxin for Treatment of Pain Associated with Temporomandibular Disorders
Focus of the Report: This report focuses on the use of botulinum toxin (BTX) for treatment of pain associated with temporomandibular disorders.
Technology Description: BTX, a neurotoxin produced by the bacterium Clostridium (C.) botulinum, is classified into 8 …