Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:
Focus of the Report: This report focuses on the use of prophylactic negative pressure wound therapy (NPWT) as an alternative to standard primary closure of open abdominal wounds following elective surgery with the goal of preventing surgical site infections (SSIs).
Technology Description:
Focus of the Report: This report focuses on the HCV-FibroSure blood test for detection and staging of liver damage in patients infected with hepatitis C virus (HCV).
Technology Description: The FibroSure test (marketed as FibroTest outside the United States) measures blood levels of bi…
Focus of the Report: Vagus nerve stimulation (VNS) is used as an adjunct to antiepileptic drugs (AEDs) for the treatment of seizures uncontrolled by medical management, epileptic surgery, or other interventions such as ketogenic diets.
Technology Description: VNS requires the surgical implantation of a pulse generator under the skin of the chest, conne…
Focus of the Report: This report focuses on the use of transcatheter mitral valve replacement (TMVR) for treating mitral regurgitation (MR), backward flow of blood due to a damaged or leaking mitral valve (MV) in the heart.
Technology Description: TMVR is a treatment for MR that uses p…
Focus of the Report: This report focuses on intradialytic parenteral nutrition (IDPN) for nutritional support in adults with end-stage renal disease (ESRD) who are undergoing hemodialysis.
Technology Description: IDPN is an intravenous infusion of essential nutrients administered durin…
Focus of the Report: The use of radiofrequency ablation (RFA) of the genicular nerves for the treatment of osteoarthritis of the knee (KOA).
Technology Description: In this report, RFA is defined as ablation of the peripheral nerves of the knee to relieve the pain associated with KOA. The …
Focus of the Report: This report focuses on the efficacy and safety of the 5-hydroxytryptamine 1F (5-HT1F) receptor agonist lasmiditan (Reyvow) for acute treatment of migraines.
Technology Description: The 5-HT1F receptors are…
Focus of the Report: This report focuses on the efficacy and safety of the calcitonin gene-related peptide (CGRP) receptor antagonist ubrogepant (Ubrelvy) for acute treatment of migraines.
Technology Description: Ubrogepant is approved for the acute treatment of migraine. Ubrogepant is a C…
Focus of the Report: This report evaluates the use of axicabtagene ciloleucel (Yescarta) for the treatment of relapsed or refractory (r/r) large B-cell lymphoma (LBCL).
Technology Description: Axicabtagene ciloleucel therapy is a form of chimeric antigen receptor (CAR) T-lymphocyte (T-…
Focus of the Report: This report focuses on fractional flow reserve (FFR), determined noninvasively via computed tomography (FFRCT), to detect coronary artery blockages, identified by coronary computed tomography angiography (CCTA), that may be responsible for myocardial ischemia in patients with known or suspected coronary artery disease (CA…