Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:
Health Problem: In the United States, it is estimated that 48 million adults have some type of hearing loss. Hearing loss can be broadly classified as sensorineural (inner ear), conductive (external and middle ear), or mixed.
Technology Description: This report evaluates the use of pe…
Health Problem: Pediatric chronic rhinosinusitis (PCRS) affects from 1.7 to 4.4 million children in the United States and is associated with an estimated annual expenditure of $1.8 billion. PCRS places a large burden of morbidity on children due to persistent symptoms, impaired sleep, multiple hospital visits, medication usage, and missed sch…
Health Problem: Advances in the technology used for the treatment of cancer have greatly improved survivorship rates in women with cancer. However, the cytotoxic effects of radiation and chemotherapy can result in premature ovarian failure and infertility, which may affect the estimated 25% of female cancer survivors of reproductive age. Estimates suggest that exposure to gon…
Health Problem: Chronic rhinosinusitis (CRS), which is the symptomatic inflammation of sinonasal mucosa, is one of the most prevalent chronic conditions, impacting from 5% to 15% of adults and costing the United States an estimated $6.9 to $9.9 billion per year. Differentiating CRS and recurrent acute rhinosinusitis (RARS) is challenging, so …
Health Problem: Trigeminal neuralgia (TGN) is a neurological condition that can cause severe pain that cannot be controlled with medication in some patients. Women are twice as likely to be affected as men and the disease most often presents after age 40 years, with a typical age of onset between 60 to 70 years.
Health Problem: Chronic rhinosinusitis (CRS), which is the symptomatic inflammation of sinonasal mucosa, is one of the most prevalent chronic conditions, impacting from 5% to 15% of adults and costing the United States an estimated $6.9 to $9.9 billion per year. Differentiating CRS and recurrent acute rhinosinusitis (RARS) is challenging, so …
Health Problem: Damage to major joints, such as the knee, hip, or spine, may be caused by diseases and conditions such as osteoarthritis, rheumatoid arthritis, fracture, bone tumors, and osteonecrosis. Symptoms associated with these conditions include persistent pain and limited function. Joint replacement surgery (arthroplasty) and associate…
Health Problem: Glioblastoma (GBM) is the most prevalent primary malignant intracranial tumor, representing as much as 16% of primary brain tumors. GBM is a fast-growing aggressive glioma that develops from glial cells in the brain. The overall prognosis is poor and even with the best standard of care, the median survival for adults with GBM …
Health Problem: Glaucoma is a disease of the optic nerve characterized by loss of retinal ganglion cells, remodeling of the lamina cribrosa, structural changes to the nerve, elevated IOP, and progressive, irreversible loss of vision leading to blindness. Open-angle glaucoma (OAG) is associated with partial blockage of the flow of aqueous humo…
Health Problem: Varicose veins are dilated, thickened, elongated, and twisted blood vessels that may appear thread-like or as grape-like clusters under the skin, most often on the legs. They are manifestations of chronic venous insufficiency, a condition characterized by dysfunction of the valves in veins, leading to increased blood pressure,…