Evidence Analysis

It is a challenge for health plans and clinicians to distill and analyze volumes of clinical evidence to determine likely clinical, financial, and risk impacts. This is what we do.

Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:

  • Does the technology improve health outcomes?
  • Are there other benefits associated with the technology?
  • What harms might be associated with the technology?
  • Have patient selection criteria been established for the technology?
  • For which patients might the technology provide a benefit?

Ultrasound Transient Elastography for Detecting Hepatic Fibrosis in Patients with Hepatitis C

Health Problem: Approximately 3.2 million people in the United States have a chronic hepatitis C virus (HCV) infection, which puts them at risk for developing hepatic fibrosis or cirrhosis, a need for liver transplantation, and possible death due to liver failure or liver cancer. However, HCV infection is a treatable disease and effective antiviral treatments that can lead to …

Rezūm System (NxThera Inc.) for Benign Prostatic Hyperplasia

Health Problem: Benign prostatic hyperplasia (BPH) is an enlargement or growth of the prostate that affects approximately 8 million men in the United States, including 30% of men older than 50 years of age and nearly 70% of men older than 70 years of age. The enlarged prostate restricts the urethra and applies pressure on the base of the bladder. This restriction of the urethr…

Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis

Health Problem: Multiple sclerosis (MS) is a potentially disabling autoimmune disease that impacts the central nervous system. MS is estimated to affect 400,000 to 1,000,000 people in the United States and 2,300,000 people worldwide.

Technology Description: During hematopoietic stem cell transplantation (HSCT), a patient undergoes a partially or fully my…

DaTscan (123I-Ioflupane; GE Healthcare) for Diagnosis and Management of Parkinson Disease

Health Problem: Parkinson disease (PD) is a neurodegenerative condition characterized by motor symptoms such as resting tremor, muscle rigidity, postural instability, and bradykinesia and nonmotor symptoms such as sleep disorders, olfactory impairment, attention/memory impairment, apathy, depression, and anxiety. The cause of PD is degeneration of the dopaminergic system due t…

Transcranial Magnetic Stimulation for the Treatment of Obsessive-Compulsive Disorder

Health Problem: Obsessive-compulsive disorder (OCD) is a disorder characterized by intrusive obsessions and repetitive compulsions where symptoms interfere with a person’s routine, occupation, or social functioning; lifetime prevalence of OCD is estimated between 2% to 3% in the United States. Repetitive transcranial magnetic stimulation (rTMS) has been proposed as an alternat…

Epidural Steroid Injections for Cervical Radiculopathy

Health Problem: Cervical radiculopathy is a condition that involves nerve root compression in the cervical spine. Causes of cervical radiculopathy include cervical degenerative disc disease, such as herniated disc, as well as spondylosis and cervical spinal stenosis. Few studies have examined the prevalence of cervical radiculopathy, but an oft-cited estimate is 83 patients di…