Evidence Analysis

It is a challenge for health plans and clinicians to distill and analyze volumes of clinical evidence to determine likely clinical, financial, and risk impacts. This is what we do.

Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:

  • Does the technology improve health outcomes?
  • Are there other benefits associated with the technology?
  • What harms might be associated with the technology?
  • Have patient selection criteria been established for the technology?
  • For which patients might the technology provide a benefit?

Flow Diverter Devices for Intracranial Aneurysms: A Review of Reviews

Purpose of Technology: Flow diverters are stents tunneled through blood vessels to the site of an intracranial aneurysm to block the blood vessel opening to the aneurysm. The stent diverts blood flow past the aneurysm opening, prohibiting inflow to the aneurysm, with the intent of causing hemostasis within the aneurysm, endothelial growth at the opening to the aneurysm, and, e…

High-Intensity Focused Ultrasound for Salvage Therapy of Recurrent Prostate Cancer

Purpose of Technology: High-intensity focused ultrasound (HIFU) is a minimally invasive (transrectal) treatment that generates heat through sound energy to destroy tumor tissue. Sound waves produced by an ultrasonic transducer mounted on an endorectal probe penetrate the rectal wall and ablate either the entire prostate gland or focal areas containing tumor while avoiding dama…

Capsule Endoscopy for the Diagnosis of Small Bowel Crohn’s Disease

Purpose of Technology: Capsule endoscopy (CE), also called wireless capsule endoscopy or video capsule endoscopy, is a minimally invasive procedure in which the patient swallows a multivitamin-sized capsule containing a miniaturized video camera, light transmitter, and batteries. The camera takes a video recording of the mucosal lining of the esophagus, small bowel, and/or col…

Occupational Therapy for Attention-Deficit/Hyperactivity Disorder (ADHD)

Purpose of Technology: Occupational therapy (OT) for attention-deficit/hyperactivity disorder (ADHD) encompasses a wide array of interventions, with the aim of increasing function in all aspects of life and settings (school, home, etc.). Specific interventions vary and are determined by the occup…

Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fractures

Purpose of Technology: Percutaneous kyphoplasty (KP) is an interventional procedure used to treat painful vertebral compression fractures related to osteoporosis. The procedure involves guided insertion of an inflatable bone tamp into the partially collapsed vertebral body. Once in place, the bal…

Antibiotic-Impregnated Bone Cement for Knee Arthroplasty

Purpose of Technology: Antibiotic bone cement (ABC) is a type of curable polymethylmethacrylate preparation created by adding various antibiotic medications to plain, nonmedicated bone cement. Most commonly, ABC is used to treat infected total joint prostheses as part of a revision arthroplasty, but its use as antibiotic prophylaxis in primary joint arthroplasty is increasing….

Proton Beam Therapy for Non-Small Cell Lung Cancer

Purpose of Technology: Proton beam therapy (PBT) is a type of external radiation treatment in which positively charged subatomic particles (protons) are precisely targeted to a specific tissue mass using a sophisticated stereotaxic planning and delivery system. In comparison with conventional photon or electron irradiation, proton beam radiation may deliver a higher dose to th…

Intravenous Immunoglobulin for the Treatment of Myasthenia Gravis

Purpose of Technology: Intravenous immunoglobulin (IVIG) has been investigated as a treatment for a variety of neurological disorders, including myasthenia gravis (MG), an autoimmune disease. The goal of IVIG for neurological disorders is to eliminate or reduce neurologic symptoms and normalize o…