Purpose of Technology: Sugammadex (SUG) is indicated for the reversal of neuromuscular blockade (NMB) induced by rocuronium bromide and vecuronium bromide during surgery. SUG selectively binds to neuromuscular blocking …
Evidence Analysis
It is a challenge for health plans and clinicians to distill and analyze volumes of clinical evidence to determine likely clinical, financial, and risk impacts. This is what we do.Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:
- Does the technology improve health outcomes?
- Are there other benefits associated with the technology?
- What harms might be associated with the technology?
- Have patient selection criteria been established for the technology?
- For which patients might the technology provide a benefit?
- Health Technology Assessments
- Evidence Analysis Research Briefs
- Evolving Evidence Review
- Clinical Research Responses
Accelerated Partial Breast Irradiation for Breast Cancer Using Brachytherapy
Purpose of Technology: Brachytherapy involves temporary implantation of radioactive materials at the site of a tumor. For treatment of breast cancer, brachytherapy is generally performed after lumpectomy. The goal of this procedure, which may be performed as an adjunct to chemotherapy or hormonot…
High-Frequency Chest Wall Compression for Cystic Fibrosis
Purpose of Technology: High-frequency chest wall compression (HFCWC) is a mechanical, external thoracic oscillatory therapy for cystic fibrosis (CF) patients whose ability to clear pulmonary secretions is impaired. The purpose of HFCWC is to promote effective airway clearance and pulmonary f…
Negative Pressure Wound Therapy for Chronic Wounds: Home Use
Purpose of Technology: Negative pressure wound therapy (NPWT) is a treatment for acute, subacute, and chronic wounds that involves the application of subatmospheric pressure to the open wound, with the goal of creating a controlled, closed wound amenable to surgical closure, grafting, or healing by secondary intention. NPWT is intended as an adjunct treatment for wounds that a…
Brachytherapy as an Adjunct to Other Types of Radiation Therapy for Breast Cancer
Purpose of Technology: Brachytherapy involves temporary implantation of radioactive materials at the site of a tumor. For treatment of breast cancer, brachytherapy is generally performed after breast-conserving surgery such as lumpectomy, either in the form of accelerated partial breast irradiati…
Comparative Effectiveness of Percutaneous Vertebroplasty Versus Sham, Conservative Treatment, or Kyphoplasty for Osteoporotic Vertebral Compression Fractures
Purpose of Technology: Percutaneous vertebroplasty (VP) for the treatment of osteoporotic fractures is the injection of bone cement into the affected vertebrae with the intent of restoring structural integrity and preventing further bone collapse. Clinical goals include reduction of pain, and imp…
Radiofrequency Ablation for Facet Joint Denervation for Chronic Low Back Pain
Purpose of Technology: Radiofrequency ablation (RFA) is a percutaneous treatment for chronic low back pain (LBP) using radiowave-induced heat to create a lesion in a spinal sensory nerve. Following a diagnostic blockade to target the affected nerve(s), radiofrequency (RF) current is applied in a …
Comparative Effectiveness Review of High-Frequency Left Repetitive Transcranial Magnetic Stimulation Versus Other Neurostimulation Approaches to Treatment-Resistant Depression
Purpose of Technology: Repetitive high-frequency left transcranial magnetic stimulation (HFL-rTMS) is a noninvasive technique that may serve as an alternative intervention for treatment-resistant depression (TRD). Brief repetitive pulses of magnetic energy are applied to the scalp via a large electromagnetic coil, thereby mo…
Radial Extracorporeal Shock Wave Therapy for Chronic Plantar Fasciitis
Purpose of Technology: Extracorporeal shock wave therapy (ESWT) is a noninvasive treatment for chronic plantar fasciitis that involves delivery of shock waves to the painful region of the heel with the goal of reducing pain, increasing function, and promoting healing of the affected soft tissue. …
Percutaneous Radiofrequency Ablation for Cervical and Thoracic Spinal Indications
Purpose of Technology: Radiofrequency ablation (RFA) is a percutaneous treatment that uses radiowave-induced heat to create a lesion in a spinal sensory nerve. Following a prognostic blockade to target the affected nerve(s), radiofrequency (RF) current is applied in a pulsed or continuous manner …