Evidence Analysis

It is a challenge for health plans and clinicians to distill and analyze volumes of clinical evidence to determine likely clinical, financial, and risk impacts. This is what we do.

Accessed through the Hayes Knowledge Center, the Evidence Analysis Solution addresses the following fundamental questions to help our clients determine coverage positions:

  • Does the technology improve health outcomes?
  • Are there other benefits associated with the technology?
  • What harms might be associated with the technology?
  • Have patient selection criteria been established for the technology?
  • For which patients might the technology provide a benefit?

Cryoablation for Treatment of Non-Small Cell Lung Cancer

Purpose of Technology

Cryoablation, also known as cryosurgery or cryotherapy, is the technique of destroying cells using subfreezing temperatures. Cryoablation of non-small cell lung cancer (NSCLC) is usually performed by an interventional radiologist t…

MRI-TRUS Fusion-Guided Biopsy for the Diagnosis of Prostate Cancer

Purpose of Technology

Magnetic resonance imaging and transrectal ultrasound (MRI-TRUS) fusion-guided biopsy uses software to combine detailed images obtained from an MRI with the less detailed real-time TRUS, through an overlaid 3-dimensional view. These “fused” images guide the placement of the biopsy needle to suspicious lesions identified from the MRI for prostate…

Primary Endovascular Mechanical Thrombectomy for Treatment of Acute Ischemic Stroke

Purpose of Technology

Mechanical thrombectomy for acute ischemic stroke involves the use of minimally invasive devices such as stent retrievers that are inserted into the femoral artery in the groin and advanced to the site of the blockage in a cerebral artery. The thrombectomy device is then activated or deployed to disrupt, push aside, or capture and retrieve the c…

Intraoperative Radiotherapy for Treatment of Early-Stage Breast Cancer

Purpose of Technology

For intraoperative radiotherapy (IORT), a single high dose of radiation is given to the tumor bed at the time of breast-conserving surgery in patients with early-stage breast cancer, which has not spread beyond the breast or lymph nodes in the armpit of the affected side. IORT is an alternative to several weeks of postoperative external-beam rad…

Sonohysterography for Assessment of Abnormal Uterine Bleeding

Purpose of Technology

Sonohysterography (SHG) is a diagnostic imaging technique used to evaluate the uterus and endometrial cavity for uterine fibroids (i.e., submucosal myomas), endometrial polyps, and intrauterine abnormalities. It is primarily used …

PCSK9 Inhibitors for Cholesterol Reduction: Evolocumab

Purpose of Technology

Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are monoclonal antibodies that target and inactivate the PCSK9 protein in the liver. This drug is intended to reduce the amount of harmful low-density lipoprotein cholesterol (LDL-C) circulating in the bloodstream,…

Ultrasound Bone Growth Stimulation

Purpose of Technology

Low-intensity pulsed ultrasound (US) bone growth stimulators apply low-intensity, pulsed, high-frequency acoustic pressure waves to a fracture site to stimulate bone growth and promote fracture healing. Bone growth stimulators have been developed to augment standard operative an…

Continuous Glucose Monitoring Systems

Purpose of Technology

Continuous glucose monitoring (CGM) systems are minimally invasive or noninvasive devices that measure glucose levels in interstitial fluid at frequent intervals over a period of several days. CGM systems are designed to obtain information regarding daily patterns in glucose levels that, when evaluated in re…