This report reviews clinical study abstracts and clinical practice guidelines addressing the use of multisyndrome panel testing to aid in the management of patients suspected of having a hereditary cancer syndrome.
Publications
Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.
See below for some of our recent publications.
Viaskin Epicutaneous Immunotherapy (EPIT) for Peanut Allergy
Viaskin Peanut is an investigational daily immunotherapy patch for treatment of peanut allergy in children aged 1 to 3 years.
Alleviant (ALV1) System (Alleviant Medical Inc.) for Heart Failure
The Alleviant (ALV1) System is a radiofrequency catheter used to create an implant-free interatrial shunt for the treatment of heart failure with preserved ejection fraction (HFpEF) or heart failure with mildly reduced ejection fraction (HFmrEF).
Guardant360 CDx (Guardant Health Inc.)
This report evaluates the impact of the Guardant360 CDx test (Guardant Health Inc.) as a companion diagnostic on patient survival.
Female-to-Male Gender-Affirming Surgical Procedures for Adolescents With Gender Dysphoria
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of female-to-male (FtM) gender-affirming surgery (GAS) for adolescents with gender dysphoria (GD).
Beremagene Geperpavec-svdt (Vyjuvek; Krystal Biotech Inc.) for Dystrophic Epidermolysis Bullosa
Vyjuvek is a topical gene therapy indicated for the treatment of wounds in patients 6 months of age and older with dystrophic epidermolysis bullosa (DEB) with mutation(s) in the collagen type VII alpha 1 chain (COL7A1) gene.
Revivent TC Transcatheter Ventricular Enhancement System (BioVentrix Inc.)
The Revivent TC Transcatheter Ventricular Enhancement System is a micro-anchor and tether system intended for minimally invasive left ventricular (LV) restoration in patients with LV scar/aneurysm and heart failure.
Reducer Coronary Sinus Implant (Shockwave Medical Inc.) for Refractory Angina
The Reducer (Shockwave Medical Inc.) is a catheter-delivered, hourglass-shaped, stainless steel mesh device implanted into the coronary sinus to improve blood flow to ischemic myocardial tissue in patients with refractory angina pectoris who are unsuitable for revascularization by coronary artery bypass grafting or percutaneous coronary intervention.
VE303 (Vedanta Biosciences Inc.) for Prevention of Recurrent Clostridioides Difficile Infection
VE303 is an investigational oral microbiome restoration therapy proposed to prevent recurrent Clostridioides difficile infection (CDI) in adults following antibacterial treatment for CDI.
Dry Needling for Mechanical Neck and/or Trapezius Muscle Pain in Adults
Focus of the Report: The focus of this Health Technology Assessment is to evaluate the effectiveness and safety of dry needling (DN) compared with standard therapies to treat chronic pain of the neck or upper trapezius in adults.
Technology Description: DN (also called intramuscular st…