Afamitresgene autoleucel (afami-cel; Adaptimmune LLC) is an intravenously administered melanoma-associated antigen A4 (MAGE-A4)-directed genetically modified autologous T cell immunotherapy indicated for the treatment of select adults with previously treated, unresectable or metastatic synovial sarcoma.
Publications
Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.
See below for some of our recent publications.
ReActiv8 Implantable Neurostimulation System (Mainstay Medical Ltd.) for Chronic Low Back Pain
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the ReActiv8 Implantable Neurostimulation System for mechanical chronic low back pain due to lumbar multifidus muscle weakness for improvements in pain, disability, quality of life, and change in opioid intake.
UX111 (Ultragenyx Pharmaceutical Inc.) for Mucopolysaccharidosis Type IIIA
UX111 (Ultragenyx Pharmaceutical Inc.) is an investigational single-infusion gene therapy proposed for the treatment of mucopolysaccharidosis type IIIA (MPS IIIA).
INO-1307 (Inovio Pharmaceuticals Inc.) for Recurrent Respiratory Papillomatosis
INO-3107 (Inovio Pharmaceuticals Inc.) is an injectable plasmid DNA immunotherapy under investigation in combination with electroporation for the treatment of recurrent respiratory papillomatosis in adults.
Verve Transurethral Renal Pelvic Denervation System (Verve Medical Inc.) for Uncontrolled Hypertension
The Verve Renal Pelvic Denervation System (formerly the Phoenix System; Verve Medical Inc.) is an investigational transurethral renal pelvic denervation system that uses a cystourethroscopic approach to perform radiofrequency ablation of the renal nerves for the treatment of uncontrolled hypertension.
CardiAMP Cell Therapy for Heart Failure
CardiAmp Cell Therapy is a cell harvesting, processing, and injection kit for transendocardial delivery of autologous bone marrow-derived cells to the heart for treatment of ischemic heart failure.
MISHA Knee System (Moximed Inc.) for Treatment of Medial Compartment Knee Osteoarthritis
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the MISHA Knee System (Moximed Inc.) for treatment of medial compartment knee osteoarthritis.
Revakinagene Tororetcel (Neurotech Pharmaceuticals Inc.) for Macular Telangiectasia Type 2
Revakinagene tororetcel (Neurotech Pharmaceuticals Inc.) is an investigational ocular implant that delivers sustained therapeutic doses of ciliary neurotrophic factor to the retina to slow the progression of macular telangiectasia type 2.
Vibrant System (Vibrant Gastro Inc.) for Treatment of Chronic Idiopathic Constipation
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the Vibrant System (Vibrant Gastro Inc.) for treatment of chronic idiopathic constipation.
Suprascapular Nerve Blockade for Treatment of Poststroke Hemiplegic Shoulder Pain
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of suprascapular nerve blockade for treatment of poststroke hemiplegic shoulder pain.