Pegcetacoplan (Syfovre; Apellis Pharmaceuticals Inc.) is a complement inhibitor indicated for the treatment of geographic atrophy secondary to age-related macular degeneration.
Publications
Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.
See below for some of our recent publications.
AGN1 Local Osteo-Enhancement Procedure (LOEP) Kit
The AGN1 Local Osteo-Enhancement Procedure (LOEP) Kit is a resorbable calcium-based implant to improve femoral bone density and strength in postmenopausal patients with osteoporosis.
OPRA Implant System (Integrum Inc.) in Patients With Transfemoral Amputation
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support use of the Osseoanchored Prostheses for the Rehabilitation of Amputees (OPRA) Implant System (Integrum Inc.) for the restoration of function in patients who are unable to use or report complications that result from conventional socket…
Electrical Impedance Spectroscopy With Nevisense (SciBase AB) for Diagnosis of Cutaneous Melanoma
Focus of the Report: The focus of this Health Technology Assessment is evaluation of the effectiveness and safety of electrical impedance spectroscopy (EIS) as an adjunct to conventional clinical examination alone or combined with dermoscopy for diagnosis of cutaneous melanoma in patients who have suspicious skin lesions.
Wendler Glottoplasty Surgery for Voice Feminization in Patients with Gender Dysphoria
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of Wendler glottoplasty (WG) surgery (anterior glottal web formation) for voice feminization in patients with gender dysphoria (GD).
Monarch eTNS System (NeuroSigma Inc.) for Treatment of Attention-Deficit/Hyperactivity Disorder in Children
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the Monarch eTNS [external trigeminal nerve stimulation] System (NeuroSigma Inc.) for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children.
TIVUS System (SoniVie) for Pulmonary Hypertension
The Therapeutic Intravascular Ultrasound System (TIVUS) is an intravascular ultrasound system under investigation for catheter-based pulmonary artery denervation to treat adult patients with pulmonary arterial hypertension.
Tofersen for Amyotrophic Lateral Sclerosis
Tofersen is an investigational antisense oligonucleotide proposed for the treatment of amyotrophic lateral sclerosis (ALS) caused by mutations in the SOD1 gene.
Minimally Invasive Lumbar Decompression Device Kit (Vertos Medical Inc.) for Treatment of Lumbar Spinal Stenosis
Focus of the Report: The focus of this Health Technology Assessment is to evaluate the effectiveness and safety of the minimally invasive lumbar decompression (mild) procedure, an approach that uses a proprietary surgical kit (mild; Vertos Medical Inc.) to treat lumbar spinal stenosis (LSS) in adult (≥ 18 years old) patients.
Coolief Cooled RF System (Avanos Medical Inc.) for Pain due to Degenerative Hip Disease
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of cooled radiofrequency ablation (CRFA) using the Coolief system (Avanos Medical Inc.) for relief of pain and improvement of function in adults with degenerative hip disease.