Omburtamab is a radiolabeled monoclonal antibody targeting tumor antigen B7-H3 in development for intraventricular radioimmunotherapy for treatment of neuroblastoma central nervous system/leptomeningeal metastases.
Publications
Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.
See below for some of our recent publications.
Computerized Dynamic Posturography for Diagnosis of Vestibular Disorders
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of computerized dynamic posturography (CDP) for diagnosing vestibular disorders in adults with signs and symptoms suggesting vestibular disorder, compared with standard otoneurologic tests. While other Hayes reports have more b…
Conventional Radiofrequency Ablation for Sacroiliac Joint Denervation for Chronic Low Back Pain
Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the effectiveness and safety of conventional (i.e., continuous, thermal) radiofrequency ablation (RFA) for sacroiliac joint (SIJ) denervation for the treatment of chronic low back pain (CLBP) thought to arise from the SIJ.
Rebyota (Fecal Microbiota, Live-jslm) for Prevention of Recurrent Clostridioides Difficile Infection
Rebyota (fecal microbiota, live-jslm) is a ready-to-use enema product for fecal microbiota transplantation indicated for the prevention of recurrence of Clostridioides difficile infection (CDI) in individuals 18 years of age and older, following antibiotic treatment for recurrent CDI.
FlowSense Device for Evaluation of Ventricular Shunt Function
The Flowsense device is a wireless, noninvasive thermal flow sensor in development for the detection of flow in implanted cerebrospinal fluid shunts in patients with hydrocephalus.
Ultrasound-Guided High-Intensity Focused Ultrasound for Primary Treatment of Localized Prostate Cancer
Focus of the Report: This Health Technology Assessment (HTA) focuses on high-intensity focused ultrasound (HIFU) for primary treatment of localized prostate cancer (PCa).
Technology Description: HIFU is a minimally invasive treatment that ablates malignant prostatic tissue using high-i…
Teplizumab-mzwv (Tzield) for the Delay of Symptomatic Type 1 Diabetes
Teplizumab is an intravenously administered anti-CD3 monoclonal antibody indicated to delay the onset of stage 3 type 1 diabetes (T1D) in adult and pediatric patients aged 8 years and older with stage 2 T1D.
Evoke Spinal Cord Stimulation System (Saluda Medical Pty Ltd.) for Chronic Intractable Pain
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the Evoke SCS System for pain reduction and decreased opioid use related to chronic intractable back and leg pain.
Barostim Neo System (CVRx Inc.) for Treatment of Heart Failure
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the Barostim Neo System (CVRx Inc.) for the treatment of heart failure (HF) to improve quality of life (QOL) and functional outcomes.
Proton Beam Therapy for Esophageal Squamous Cell Carcinoma
Focus of the Report: The focus of this Health Technology Assessment (HTA) is to evaluate the effectiveness and safety of proton beam therapy (PBT) compared with conventional (photon-based) external beam radiation therapies to treat esophageal squamous cell carcinoma (ESCC) in adults.
Technolo…