Publications

Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.

Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.

See below for some of our recent publications.

GammaSense Stimulation System for Alzheimer Disease

The GammaSense Stimulation System is an investigational, home-use, wearable device that delivers auditory and visual stimulation to entrain gamma frequency neural activity in the brain. It is proposed for the treatment of mild to moderate Alzheimer disease (AD). Brainwave entrainment is a technique to prompt the brain’s neural activity to synchronize to the frequency of exter…

Organ Care System (OCS) Heart

The OCS Heart is a portable extracorporeal heart perfusion and monitoring system indicated for the preservation of donation-after-brain-death (DBD) donor hearts deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of prolonged cold static cardioplegic preservation (e.g., > 4 hours of cross-clamp time); and for the ex vivo reanimation,…

External Female Catheters

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of external urinary catheters in inpatient hospital or residential care settings to reduce the incidence of catheter-associated urinary tract infection (CAUTI) in patients with female genitalia and urinary incontinence (UI).

Percutaneous Peripheral Nerve Stimulation for Treatment of Chronic Pain

Focus of the Report: This report focuses on percutaneous peripheral nerve stimulation (PNS) therapy utilizing an external pulse generator for the treatment of adults with intractable chronic pain (pain persisting for ≥ 3 months).

Technology Description: Percutaneous PNS is a nonpharmac…

Fecal Microbiota Transplantation for the Treatment of Crohn Disease

Focus of the Report: The focus of this Health Technology Assessment is to evaluate the safety and effectiveness of fecal microbiota transplantation (FMT) to treat patients with Crohn disease (CD).

Technology Description: FMT is a procedure by which processed stool from healthy donors i…

Freespira Digital Therapeutic (Freespira Inc.) for Treatment of Panic Disorder

This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the Freespira biofeedback device to reduce the need for acute care, lessen panic symptom severity, and decrease the number of panic attacks in adults with panic disorder.