Pyrukynd (mitapivat) is an oral pyruvate kinase activator indicated for the treatment of hemolytic anemia in adults with pyruvate kinase (PK) deficiency.
Publications
Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.
See below for some of our recent publications.
Impella Heart Pumps for Cardiac Support in Patients Undergoing High-Risk Percutaneous Coronary Intervention
Focus of the Report: The focus of this Health Technology Assessment is to evaluate the safety and effectiveness of Impella devices for hemodynamic support during high-risk percutaneous coronary intervention (HRPCI).
Technology Description: The Impella 2.5, Impella CP (Cardiac Power), a…
The Tether (Zimmer Biomet) for Skeletally Immature Patients With Progressive Idiopathic Scoliosis
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of vertebral body tethering (VBT) with The Tether (Zimmer Biomet Spine Inc.) for correcting spinal curvature in skeletally immature patients with progressive idiopathic scoliosis.
Dexcom G6 (Dexcom, Inc.) Continuous Glucose Monitoring System for Type 2 Diabetes Mellitus
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the Dexcom G6 Continuous Glucose Monitoring System for the management of adult patients with type 2 diabetes mellitus.
MindMotion GO (MindMaze) for Stroke Telerehabilitation
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of MindMotion GO (MindMaze) for stroke telerehabilitation to improve motor function.
Rethymic (Enzyvant Therapeutics Inc.) for Congenital Athymia
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of Rethymic (Enzyvant Therapeutics Inc.) for increased longevity and immune reconstitution in pediatric patients with congenital athymia.
Luminopia One for Amblyopia in Children
The Luminopia One is a software-only digital therapeutic used with commercially available head-mounted displays intended for home use for improvement in visual acuity in amblyopia patients aged 4-7 years associated with anisometropia and/or with mild strabismus, having received treatment instructions (frequency and duration) as prescribed by a trained eye care professional.
Xaracoll (Innocoll Pharmaceuticals Ltd.) for Analgesia for Open Inguinal Hernia Repair
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of Xaracoll implants for acute post-surgical pain management following open inguinal hernia repair.
DecisionDx-Melanoma
This report evaluates the analytical validity, clinical validity, and clinical utility of the DecisionDx-Melanoma test.
InSpace Biodegradable Subacromial Spacer (Stryker) for Irreparable Rotator Cuff Tears
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of the InSpace biodegradable subacromial spacer (Stryker) to reduce pain and improve function and quality of life for adults with irreparable rotator cuff tears.