This report reviews clinical study abstracts and clinical practice guidelines addressing genetic testing for hereditary spastic paraplegia (HSP).
Publications
Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.
See below for some of our recent publications.
Superion Interspinous Spacer System (Vertiflex) for Treatment of Neurogenic Claudication Caused by Spinal Stenosis
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of Superion Interspinous Spacer System (Vertiflex) for the treatment of neurogenic claudication related to lumbar spinal stenosis resulting in pain relief, improvement in back-specific function, and quality of life.
GeneSight Psychotropic (Assurex Health Inc./Myriad Neuroscience)
This report evaluates the analytical validity, clinical validity, and clinical utility of the GeneSight Psychotropic (Myriad Neuroscience) test.
Kerendia (Finerenone) for Diabetic Kidney Disease
Kerendia (finerenone) is a nonsteroidal mineralocorticoid receptor antagonist indicated to reduce the risk of sustained estimated glomerular filtration rate (eGFR) decline, end stage kidney disease, cardiovascular death, non-fatal myocardial infarction, and hospitalization for heart failure in adult patients with chronic kidney disease associated with type 2 diabetes.
T-Cell Receptor (TCR) Gene Rearrangement Testing for Mature/Peripheral T-Cell Lymphoma
This report reviews clinical study abstracts and clinical practice guidelines addressing molecular testing for monoclonal T-cell receptor (TCR) gene rearrangements to aid diagnosis and/or staging of mature/peripheral T-cell lymphoma.
Axonics Sacral Neuromodulation (Axonics Inc ) for the Management of Urinary Dysfunction
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of Axonics Sacral Neuromodulation (Axonics Modulation Technologies Inc.) for the management of urinary dysfunction.
Vivistim Paired VNS System for Stroke Rehabilitation
The Vivistim Paired VNS System is an implanted neurostimulator system intended to be used to stimulate the vagus nerve during rehabilitation therapy in order to reduce upper extremity motor deficits and improve motor function in chronic ischemic stroke patients with moderate to severe arm impairment.
Intravascular Lithotripsy (IVL) System with C2 Coronary IVL Catheter (Shockwave Medical Inc.) for Calcified Coronary Lesions
This report addresses whether full-text clinical studies, systematic reviews, and clinical practice guidelines and position statements support the use of intravascular lithotripsy (IVL) for treatment of calcified arteries in patients with coronary artery disease (CAD).
Fecal Calprotectin Assay for Monitoring Disease Activity and Treatment Management of Ulcerative Colitis in Adults
Focus of the Report: This report focuses on fecal calprotectin (FC) testing to monitor disease activity and guide therapy choices in patients who have ulcerative colitis (UC).
Technology Description: Calprotectin is a calcium-binding protein that is abundant in neutrophils. During acti…
Fecal Calprotectin for Predicting Clinical Relapse or Treatment Response in Adult Patients with Ulcerative Colitis
Focus of the Report: This report focuses on fecal calprotectin (FC) testing for determining the prognosis of disease activity (i.e., predicting clinical relapse) in patients who are undergoing treatment for ulcerative colitis (UC).
Technology Description: Calprotectin is a calcium-bind…