Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.
See below for some of our recent publications.
Focus of the Report: This report evaluates the use of liquid sublingual immunotherapy (SLIT) for the treatment of allergic rhinitis in the United States.
Technology Description: Liquid SLIT involves the daily administration of a diluted dose of an allergen under the tongue, which allow…
Focus of the Report: This report focuses on Eustachian tube balloon dilation (ETBD) for treatment of adults with chronic Eustachian tube dysfunction (ETD) refractory to medical management (MM).
Technology Description: ETBD is a minimally invasive transnasal endoscopic procedure in whic…
Evkeeza (evinacumab-dgnb) is an ANGPTL3 (angiopoietin-like 3) inhibitor indicated as an adjunct to other low-density lipoprotein cholesterol (LDL-C) lowering therapies for the treatment of adult and pediatric patients, aged 12 years and older, with homozygous familial hypercholesterolemia (HoFH).
The eXciteOSA Daytime Therapy Device (formerly known as Snoozeal) is a noninvasive electrical muscle stimulation device that delivers electrical pulses through a mouthpiece that sits around the tongue. The system consists of a mouthpiece, a rechargeable control unit that connects to the mouthpiece via a USB interface, and a mobile app that allows the user to control and track…
Focus of the Report: This report focuses on the use of prophylactic negative pressure wound therapy (NPWT) as an alternative to standard primary closure of open abdominal wounds following elective surgery with the goal of preventing surgical site infections (SSIs).
Technology Description:
Focus of the Report: This report focuses on the HCV-FibroSure blood test for detection and staging of liver damage in patients infected with hepatitis C virus (HCV).
Technology Description: The FibroSure test (marketed as FibroTest outside the United States) measures blood levels of bi…
Lupkynis (voclosporin) is an oral calcineurin-inhibitor immunosuppressant indicated in combination with a background immunosuppressive therapy regimen for the treatment of adult patients with active lupus nephritis (LN).
Focus of the Report: Vagus nerve stimulation (VNS) is used as an adjunct to antiepileptic drugs (AEDs) for the treatment of seizures uncontrolled by medical management, epileptic surgery, or other interventions such as ketogenic diets.
Technology Description: VNS requires the surgical implantation of a pulse generator under the skin of the chest, conne…
This report evaluates the clinical utility of whole genome sequencing (WGS) and whole exome sequencing (WES) in patients with a primary phenotype of intellectual disability (ID). In general, ID may be associated with other neurological disorders, various genetic syndromes, and autism spectrum disorders. However, this report focuses on patients whose primary phenotype of conce…
Focus of the Report: This report focuses on the use of transcatheter mitral valve replacement (TMVR) for treating mitral regurgitation (MR), backward flow of blood due to a damaged or leaking mitral valve (MV) in the heart.
Technology Description: TMVR is a treatment for MR that uses p…