Publications

Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.

Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.

See below for some of our recent publications.

Expandable Interbody Cages for Cervical Spinal Fusion

Focus of the Report: This Health Technology Assessment focuses on expandable interbody cages (EICs) for cervical fusion in patients with degenerative disc disease (DDD).

Technology Description: Interbody fusion procedures involve the removal of a pathologic disc and insertion of interbody cages and bone grafts, with the aim of stabilizing the spine by …

ColonSentry (Stage Zero Life Sciences)

The report evaluates the analytical validity, clinical validity, and clinical utility of the ColonSentry liquid biopsy test, a gene expression assay intended to estimate the current relative risk of having colorectal cancer (CRC) for patients eligible for CRC screening.

Minimally Invasive Procedures for Thyroidectomy

Focus of the Report: This report focuses on minimally invasive techniques for thyroidectomy.

Technology Description: For minimally invasive thyroid surgery, patients are placed under general anesthesia and the procedure is performed through small incisions in the neck, breast, armpits,…

Botulinum Toxin for Treatment of Gastroparesis

Focus of the Report: Use of botulinum toxin (BTX) for treatment of gastroparesis.

Technology Description: BTX, a neurotoxin produced by the bacterium Clostridium botulinum, inhibits the release of the neurotransmitter acetylcholine at the neuromuscular junction and causes muscle paralysis. B…

Concentrated Bone Marrow Aspirate for Spinal Surgery

Focus of the Report: This report evaluates the use of autologous concentrated bone marrow aspirate (CBMA) for spinal fusion surgeries.

Technology Description: Autologous CBMA may be implanted during spinal fusion procedures alone or as an adjunct to other bone grafting materials. CBMA …

Chloroquine and Hydroxychloroquine for COVID-19

Chloroquine (and its metabolite, hydroxychloroquine) is an oral 4-aminoquinoline antimalarial agent that has demonstrated antiviral effects on SARS-CoV and SARS-CoV-2 in vitro. It is being evaluated for the treatment of COVID-19.