Publications

Hayes Publications are available through the Hayes Knowledge Center, a portal to world-class research and unbiased analyses on the clinical, financial, and risk impacts of emerging, controversial, and disruptive healthcare technologies.

Every Hayes publication is developed by multidisciplinary teams of clinicians and scientists using rigorous methods grounded in internally recognized standards for systematic review and Health Technology Assessment. Learn more about these evidence resources and see sample titles below.

See below for some of our recent publications.

Zeposia (Ozanimod) for Relapsing Forms of Multiple Sclerosis

Zeposia (ozanimod) is an oral sphingosine-1 phosphate (S1P) receptor modulator indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Cellular Skin Substitutes for Chronic Foot Ulcers in Adults with Diabetes Mellitus

Health Problem: Diabetes mellitus (DM) can damage blood vessels, compromising blood flow and oxygen circulation. Resulting tissue hypoxia may contribute to failure of even minor wounds to heal. Chronic foot ulcers in people with DM (DFU) may occur when foot injuries, such as cuts, blisters, or sores, develop, worsen, and do not heal. Reasons …

Prokera (Bio-Tissue Inc.) for Treatment of Ocular Indications

Focus of the Report: This report evaluates the use of the ProKera device (Bio-Tissue Inc.) for the treatment of ocular indications.

Technology Description: ProKera is comprised of a cryopreserved human amniotic membrane graft that is fastened to an ophthalmic conformer without the use …