This report evaluates the clinical utility of methylenetetrahydrofolate reductase (MTHFR) genotyping in pediatric or adult patients to detect rare variants associated with severe MTHFR enzyme deficiency for the purpose of informing treatment or family-planning decisions.
Precision Medicine
The explosion of genetic and molecular medicine has produced mountains of options and evidence. Conversely, there is often an alarming lack of evidence. This is where we come in.We help you manage the flood of tests and drugs that emerge in this category daily. Accessed through the Hayes Knowledge Center, our comprehensive Precision Medicine solution focuses on thousands of genetic, genomic, and molecular diagnostic tests and precision medicine therapies addressing the questions our clients most frequently ask:
- Will testing change patient management for this indication?
- If so, what tests and/or therapies should I use?
- Should we cover testing and/or therapies?
- Can we manage these services internally?
- Precision Medicine Insights
- Precision Medicine Research Briefs
Genetic Testing for Patients With Clinically Diagnosed Autism Spectrum Disorder
This report evaluates the clinical utility of genetic testing for patients with clinically diagnosed autism spectrum disorder (ASD) and their first-degree relatives to determine genetic etiology, inform patient management, and improve outcomes.
Cxbladder Detect (Pacific Edge Ltd.)
This report evaluates the clinical validity and clinical utility of the Cxbladder Detect test (Pacific Edge Ltd.).
FoundationOne Heme (Foundation Medicine Inc.)
This report evaluates the clinical validity and clinical utility of the FoundationOne Heme test.
NavDx (Naveris)
This report evaluates the clinical validity and clinical utility of the NavDx test.
Vectra (Laboratory Corporation of America Holdings)
This report evaluates the clinical validity and clinical utility of the Vectra test (Laboratory Corporation of America Holdings).
Cxbladder Monitor (Pacific Edge Ltd.)
This report evaluates the clinical validity and clinical utility of the Cxbladder Monitor test.
Multitarget Panels for Identification of Vaginal Pathogens
Percepta Genomic Sequencing Classifier (Veracyte Inc.)
This report evaluates the clinical validity and clinical utility of the Percepta Genomic Sequencing Classifier (GSC) test (Veracyte Inc.).
Multisyndrome Panel Testing to Aid in Management of Patients Suspected of Having a Hereditary Cancer Syndrome
This report reviews clinical study abstracts and clinical practice guidelines addressing the use of multisyndrome panel testing to aid in the management of patients suspected of having a hereditary cancer syndrome.